Page 48 - CnO_253-254

D ALLE AREE - SC OMPENSO C ARDIA C O

D.; Allen, L.A.; Byun, J.J.; Colvin, M.M.; fraction. Eur. Heart J. 2014, 35, 3442– https://doi.org/10.1038/s41569-021-
Deswal, A.; Drazner, M.H.; Dunlay, 3451. 00605-5.
S.M.; Evers, L.R.; et al. 2022 AHA/ACC/ https://doi.org/10.1093/eurheartj/ehu254. 19. Manca, P.; Stolfo, D.; Merlo, M.;
HFSA Guideline for the Management of 14. D’Elia, E.; Vaduganathan, M.; Gori, Gregorio, C.; Cannatà, A.; Ramani, F.;
Heart Failure: A Report of the American M.; Gavazzi, A.; Butler, J.; Senni, M. Nuzzi, V.; Lund, L.H.; Savarese, G.;
College of Cardi-ology/American Heart Role of biomarkers in cardiac structure Sinagra, G. Transi-ent versus persistent
Association Joint Committee on Clinical phenotyping in heart failure with improved ejection fraction in non-
Practice Guidelines. J. Am. Coll. Cardiol. preserved ejection fraction: Critical ischaemic dilated cardiomyopathy. Eur. J.
2022, 79, e263–e421. appraisal and practical use. Eur. J. Heart Heart Fail. 2022, 24, 1171–1179. https://
https://doi.org/10.1016/j. Fail. 2015, 17, 1231–1239. doi.org/10.1002/ejhf.2512.
jacc.2021.12.012. https://doi.org/10.1002/ejhf.430. 20. Halliday, B.P.; Wassall, R.; Lota, A.S.;
9. Gori M, Marini M, Gonzini L, Carigi 15. Quarta, G.; Gori, M.; Iorio, A.; Khalique, Z.; Gregson, J.; Newsome,
S, De Gennaro L, Gentile P, Leonardi D’Elia, E.; Moon, J.C.; Iacovoni, A.; S.; Jackson, R.; Rahneva, T.; Wage,
G, Orso F, Tinti D, Lucci D, Iacoviello Burocchi, S.; Schelbert, E.B.; Brambilla, R.; Smith, G.; et al. Withdrawal of
M, Navazio A, Ammirati E, Municinò P.; Sironi, S.; et al. Cardiac magnetic pharmacological treatment for heart
A, Benvenuto M, Cassaniti L, Tavazzi failure in patients with recovered
L, Maggioni AP, De Maria R; Italian dilated cardiomyopathy (TRED-HF):
Network on Heart Failure (IN-HF) Rispetto a nessun/ An open-label, pilot, randomised trial.
Investigators. Combined Neuro-Humoral Lancet 2019, 393, 61–73. https://doi.
Modulation and Outcomes in Patients singolo blocco neuro- org/10.1016/S0140-6736(18)32484-X.
with Chronic Heart Failure and Mildly 21. Solomon, S.D.; Vaduganathan, M.;
Reduced or Preserved Ejection Fraction. J umorale, il blocco Claggett, B.L.; de Boer, R.A.; DeMets,
Clin Med. 2022 Nov 8;11(22):6627. doi: D.; Hernandez, A.F.; Inzucchi, S.E.;
10.3390/jcm11226627. triplo, ma non il Kosiborod, M.N.; Lam, C.S.P.; Martinez,
10. Solomon, S.D.; McMurray, J.J.V.; F.; et al. Baseline Characteristics of
Anand, I.S.; Ge, J.; Lam, C.S.P.; doppio, ha portato a Patients With HF With Mildly Reduced
Maggioni, A.P.; Martinez, F.; Packer, and Preserved Ejection Frac-tion:
M.; Pfeffer, M.A.; Pieske, B.; et al. migliori outcome sia DELIVER Trial. JACC Heart Fail. 2022,
PARAGON-HF Investigators and 10, 184–197.
Committees. Angiotensin-Neprilysin in pazienti HFmrEF https://doi.org/10.1016/j.
Inhibition in Heart Failure with Preserved che in quelli affetti da jchf.2021.11.006.
Ejection Fraction. N. Engl. J. Med. 2019, 22. Dewan, P.; Jackson, A.; Lam,
381, 1609–1620. HFpEF C.S.P.; Pfeffer, M.A.; Zannad, F.; Pitt,
https://doi.org/10.1056/NEJMoa1908655. B.; Solomon, S.D.; McMurray, J.J.V.
11. Yusuf, S.; Pfeffer, M.A.; Swedberg, Interactions between left ventricular
K.; Granger, C.B.; Held, P.; McMurray, ejection fraction, sex and effect of
J.J.; Michelson, E.L.; Olofsson, B.; resonance in heart failure with preserved neurohumoral modulators in heart
Ostergren, J. CHARM Investigators and ejection fraction: Myocyte, interstitium, failure. Eur. J. Heart Fail. 2020, 22, 898–
Committees. Effects of candesartan in microvascular, and met-abolic 901. https://doi.org/10.1002/ejhf.1776
patients with chronic heart failure and abnormalities. Eur. J. Heart Fail. 2020, 23. Pagnesi M, Metra M, Cohen-Solal
preserved left- ven-tricular ejection 22, 1065–1075. A, Edwards C, Adamo M, Tomasoni D,
fraction: The CHARM-Preserved Trial. https://doi.org/10.1002/ejhf.1961. Lam CSP, Chioncel O, Diaz R, Filippatos
Lancet 2003, 362, 777–781. https://doi. 16. Gori, M.; Lam, C.S.; Gupta, G, Ponikowski P, Sliwa K, Voors AA,
org/10.1016/S0140-6736(03)14285-7. D.K.; Santos, A.B.; Cheng, S.; Shah, Kimmoun A, Novosadova M, Takagi
12. Pitt, B.; Pfeffer, M.A.; Assmann, A.M.; Claggett, B.; Zile, M.R.; K, Barros M, Damasceno A, Saidu H,
S.F.; Boineau, R.; Anand, I.S.; Claggett, Kraigher-Krainer, E.; Pieske, B.; et al. Gayat E, Pang PS, Celutkiene J, Cotter
B.; Clausell, N.; Desai, A.S.; Diaz, R.; PARAMOUNT Investigators. Sex-specific G, Mebazaa A, Davison B. Uptitrating
Fleg, J.L.; et al. TOPCAT Investigators. cardiovascular structure and function Treatment After Heart Failure
Spironolactone for heart failure with in heart failure with preserved ejection Hospitalization Across the Spectrum of
preserved ejection fraction. N. Engl. J. fraction. Eur. J. Heart Fail. 2014, 16, Left Ventricular Ejection Fraction. J Am
Med. 2014, 370, 1383–1392. https://doi. 535–542. https://doi.org/10.1002/ejhf.67. Coll Cardiol. 2023 Jun 6;81(22):2131-
org/10.1056/NEJMoa1313731. 17. Groenewegen, A.; Rutten, F.H.; 2144.
13. Gori, M.; Senni, M.; Gupta, Mosterd, A.; Hoes, A.W. Epidemiology doi: 10.1016/j.jacc.2023.03.426.
D.K.; Charytan, D.M.; Kraigher- of heart failure. Eur. J. Heart Fail. 2020,
Krainer, E.; Pieske, B.; Claggett, B.; 22, 1342–1356. https://doi.org/10.1002/
Shah, A.M.; Santos, A.B.; Zile, M.R.; ejhf.1858.
et al. PARAMOUNT Investigators. 18. Savarese, G.; Stolfo, D.; Sinagra, G.;
Association between renal function and Lund, L.H. Heart failure with mid-range
cardiovascular structure and function or mildly reduced ejection fraction. Nat.
in heart failure with preserved ejection Rev. Car-diol. 2022, 19, 100–116.

46 | Cardiologia negli Ospedali | duecentocinquantatre - duecentocinquantaquattro