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nel tempo. Infatti, è noto che i pazienti Inter Med 2000;160:325-32. Faggiano M,Comaschi M, Faglia E, Maggio-
diabetici con Scompenso Cardiaco 7) A trial of the beta-bloker bucindolol in ni AP. Diabete Mellito,disfunzione ventri-
patients with advanced chronic heart failu-
colare sinistra e Scompenso Cardiaco.Ital
conclamato presentano una prognosi re.The Beta- Bloker Evaluation of Survival Heart J Suppl Agosto 2004.Vol 5:605-15.
peggiore rispetto ai non diabetici: Trial Investigators. N Engl J Med 2001;344: 19) Jong P, Yusuf S, Rousseau MF,Ahn SA,
BangdiwalaSI. Effect of enalapril on 12-year
1659-67.
pertanto i trattamenti farmacologici 8) The CONSENSUS Trial Group. Effects survival and life expectancy in patients with
anti - scompenso oggi disponibili, of enalapril on mortality in severe congesti- left ventricular systolic dysfunction.a follow-
assieme ad un più stretto controllo ve heart failure. Results of the Cooperative up syudy.Lancet 2003;361:1843-8.
North Scandinavian Enalapril Survival
20) Nielsen OW, Hansen JF,Hilden
glicemico, ad una azione sinergica di Stydy (CONSENSUS). N Engl J Med ,J,Larsen CT, SvanegaardJ. Risk assessment
più figure specialistiche, alla “formazio- 1987;316:1429-35. of left ventricular systolic dysfunction in pri-
9) Digitalis Investigation Group. The effect
mary care:cross sectional study evaluating a
ne ed informazione” del paziente per il of digoxin on mortality and morbidity in range of diagnostic test. BMJ 2000;320:220-
monitoraggio domiciliare di alcuni patients whit heart failure.N Engl J Med 4.
1997;336:525-33.
21) Kannel WB, D’agostino RB, Silbershatz
parametri - sentinella di riesacerbazio- 10) Pitt B, Segal R, Martinez FA, et al. Ran- H, Belanger AJ,Wilson PW,Levy D. Profile
ne di malattia (peso corporeo, diuresi, domised trial of losartan versus captopril in for estimating risk of heart failure. Arch
patients over 65 with heart failure (Eva-
Intern Med 1999;159:1197-204.
introito idrico giornaliero, uso di sale luation of Losartan in the Elderly Study, 22) Ferrua S et al. Interazioni tra Scom-
nella dieta, pressione arteriosa, ecc.) ELITE). Lancet 1997;349:747-52. penso Cardiaco e Diabete mellito:revisione
potrebbero essere in grado di contribu- 11) Pitt B, Poole-Wilson PA, Segal R et al. critica della letteratura.Ital Heart J Suppl
Effect of losartan compared with captopril
Nov 2001.Vol2:11921200.
ire, oltre che all’approfondimento on mortality in patients with symptomatic 23) Buller GK, Perazella M. ACE inhibi-
delle conoscenze sul binomio Diabete heart failure. Randomised trial: the Losar- tor-induced hypoglycaemia. Am J Med
1991;91:104-5.
tan Heart Failure Survival Study ELITE II.
- insufficienza cardiaca, ad un aggior- Lancet 2000;355:1582-7. 24) Shindler DM, Kostis JB, Yusuf S, et al.
namento continuo e tempestivo della 12) Julian DG, Camm AJ, Frangin G, et al. Diabetes Mellitus, a predictor of morbidity
and mortality in the Studies of Left Ven-
Randomised trial of effect of amiodarone
posologia farmacologia e ad un più on mortality in patients with left ventricular tricular Dysfunction (SOLVD) Trials and
razionale accesso alle Strutture ospeda- dysfunction after recent myocardial infarc- Registry. Am J Cardiol 1996;77:1017-20.
tion: EMIAT. European Myocardial Infarct
25) Yusuf S, Sleight P, Pogue J, Bosch J, Da-
liere con una conseguente riduzione Amiodarone Trial Investigators. Lancet vies R, Dagenais G. Effects of an angioten-
delle ospedalizzazioni, e di eventi 1997:349:667-74. sin-converting-enzyme inhibitor, ramipril,
cardiovascolari. 13) Hjalmarson A, Goldstein S, Fager- on cardiovascular events in high-risk
berg B, et al. Effect of controlled-release
patients. The Heart Outcomes Prevention
metoprolol on total mortality, hodpitaliza- Evaluation Study Investigators. N Engl J
Bibliografia: tions and well-being in patients with heart Med 2000;342:143-53.
1) King H, Aubert RE, Herman WH. Global failure.The Metoprolol CR/XL Randomi- 26) Pollare T, Lithell H, Morlin C, Pranta-
burden of diabetes, 1995-2025.Prevalence, zed Intervention Trial in Congestive Heart re H, Hvarfner A, Ljunghall S. Metabolic ef-
numerical estimates, and projections. Dia- Failure. JAMA 2000;283:1295-302. fects of diltiazem and atenolol: results from
betes Care 1998; 21.1414-31. 14) Pfeffer MA, Braunwald E, Moye LA, a randomized. Double-blind study with
2) Bagust A, Hopkinson PK, Maslove L, et al, for the SAVE Investigators.Effect of parallel groups. J Hypertens 1989;7:551-9.
Currie CJ. The projected health care bur- captopril on mortality and morbidity in 27) Lithell H, Pollare T, Vessby B, Metabo-
den of type 2 diabetes in the UK from 2000 patients with left ventricular dysfunction lic effects of pindolol and propranolol in a
to 2060.Diabet Med 2002;19 (Suppl 4):1-5 after myocardial infarction. N Engl J Med double-blind cross-over study in hypertensi-
3) Clarke P, Gray A, Legood R,Briggs A, 1992;327:669-77. ve patients. Blood Press 1992;1:92-101.
Holman R. The impact of diabetes-related 15) SOLVD Investigators. Effect of enala- 28) Bristow MR, Gilbert EM, Abraham WT,
complications on healthcare costs:results pril on m ortality and the development of et al. Effect of carvedilol on left ventricular
from the United Kingdom Prospective Dia- heart failure in asymptomatic patients with function and mortality in diabetic versus
betes Study (UKPDS Study No.65). Diabet reduced left ventricular ejection fractions. non-diabetic patients with ischaemic or
Med 2003;20:442-50 N Engl J Med 1992; 327:685-91. non-ischaemic dilated cardiomiopathy.
4) Senni M, Tribouilloy CM, Rodeheffer RJ, 16) SOLVD Investigators. Effect on ena- (abstr). Eur Heart J 1996;17:P 450.
et al. Congestive heart failure in the com- lapril on survival in patients with reduced 29) Rengtsson C, Blohme G, Lapidus L.
munity. Arch Intern Med 1999; 159:29-34. left ventricular ejection fractions and Do Antihypertensive drugs precipitate
5) Amato L, Paolisso G, Cacciatore F, et congestive heart failure. N Engl J Med diabetes? BMJ 1984;289:1495-7.
al. Congestive heart failure predicts the 1991;325:393-302. 30) Donahue R, Abbott R, Wilson P. Effect
development of non-insulin-dependent 17) Cohn JN, Ziesche S, Smith R et al,. of diuretic use on the development of
diabetes mellitus in the elderly. Diabetes Effect of the calcium antagonist felodipine diabetes mellitus: in the Framingham study.
Metab 1997;23:213-8. as supplementary vasodilator therapy in Horm Metab Res 1990;22:46-8.
6) Polanczyk CA, Rohde LEP, Dec GW, patients with chronic heart failure treated 31) Helderman J, Elahi D, Anderson D.
DiSalvo T. Ten-year trends in hospital care with enalapril. V-HeFTIII. Circulation Prevention of the glucose intolerance of
for congestive heart failure. Improved out- 1997;96:856-63. thiazide diuretics by maintenance of body
comes and increased use of resources. Arch 18) Tarantini L, Di Lenarda A, Velussi M, potassium. Diabetes 1983;32:106-11.
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